 |
Integrated database
A critical component of the complex analyses is data analysis and integration, and finally the prioritization of candidates for diagnostic. For data management a web-based biomedical research network and centralised data warehouse will be customised according to the specific needs of the partners. In this context, UD-GenoMed Ldt. will provide infrastructure, training and support. Data Collection Platform: The structure of database will be customised the specific requirements and needs for data collection will be discussed by the partners, and together will defined ehe central patient registry, electronic case report forms, user-role-rights and communication management for secured access. The web-based technology will substantially increase research competitiveness by facilitating online information flow, data exchange and the improvement of the quality of data. Data Warehouse: The data warehouse, which is defined as a subject-oriented, integrated, non-volatile and expert-interpreted collection of integrated data, is the main repository, where all information is stored after processing the project relevant data sources provided by project partners and/or external available resources. The raw data records are cleaned and enriched with more detailed information. Data Mining: In the order of define target or market candidates we are going to apply statistical and data mining methods with various classifications and clustering strategies. Candidate statistical predictors and classifiers will be assessed for plausibility in cooperation with the medical and experimental groups.
Data Interpretation: The final step focuses on the identification and interpretation of the involved biological processes and molecules. In this context, a variety of tools for multidimensional data evaluation, pathway visualization and modelling of their molecular interactions will be developed by UD-GenoMed and applied.
|
